Deliver “medicines that matter” for patients

Vision

A Future Where Every Disease Has a Solution:

SFG SCIENCES envisions a future where every disease has a solution. Our commitment is to relentlessly pursue scientific breakthroughs in drug discovery, offering hope and healing to individuals and families affected by health challenges.

Mission

Harnessing Science for Life-Changing Medications:

At SFG SCIENCES, our mission is to harness the power of scientific discovery to develop and deliver life-changing medicines. We are committed to pushing the boundaries of drug development to create therapies that make a meaningful impact on patients' lives.

Team

  • Leadership
  • Board of Directors
  • Entrepreneur in Residence
  • Advisory Board

Hiroshi Nagabukuro

Chief Executive Officer

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Dr. Hiroshi Nagabukuro is SFG’s co-founder, Chief Executive Officer (CEO) and board chair. Dr. Nagabukuro also serves as CEO of Juro Sciences, one of SFG’s portfolio companies. He brings over 25 years of industry experience, leading and building teams that have strong track records of discovering and developing novel therapeutics. Prior to SFG, he co-founded ARTham Therapeutics as COO/CSO followed by CEO role, and strategically and operationally led the company until its acquisition by Kaken Pharmaceutical in 2021. Before ARTham, Dr. Nagabukuro was Senior Director of Innovation & Entrepreneurship at Takeda, where he was heading the Entrepreneurship Venture Program and contributed launches of 9 different biotech companies. Prior to Takeda, he was Research Fellow at Merck Research Laboratories, where he led multiple target identification/validation and optimization programs and significantly contributed to the adrenergic β3 program, which resulted in the approval of vibegron for overactive bladder indication. Dr. Nagabukuro also serves as an Adjunct Professor at Tohoku University Hospital. He received his PhD from the University of Tokyo.

Akira Tanaka

Chief Scientific Officer

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Dr. Akira Tanaka is a SFG’s co-founder, serves as Chief Scientific Officer and a board director. Before the inception of SFG, Dr. Tanaka was the Vice President of Clinical Science at ARTham Therapeutics where he led the clinical development, conducted Phase I and Phase II studies for two products, and contributed to obtaining a POC for one of them. Prior to ARTham, he worked in preclinical drug discovery research as a pharmacologist at Takeda and thereafter in clinical development as a clinical scientist in gastrointestinal therapeutic area at Takeda Boston site. He received his PhD from the University of Tsukuba.

Kyohei Tanaka

Chief Financial Officer

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Mr. Kyohei Tanaka is SFG’s co-founder, serves as Chief Financial Officer and a board director. Before the inception of SFG, Mr. Tanaka led the M&A exit of ARTham Therapeutics in 2021 as the Financial Advisor. He started his career at KPMG Azsa Co., and from 2005, he engaged in advisory services for domestic and international M&A transactions at the investment banking division in Nikko Citigroup and CitigroupinJapan. Subsequently, he worked at a private equity fund in Japan before founding investment hub Corporation in 2018, where he serves as CEO, providing startups with support in financing, capital strategy, and M&A exits. Mr. Tanaka graduated from the Faculty of Agriculture at the University of Tokyo and is Japan’s Certified Public Accountant.

Kanako Kuniyeda

Executive Director,
Biology

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Dr. Kanako Kuniyeda is a SFG’s co-founder and serves as an executive director (Biology). Before the inception of SFG, Dr. Kuniyeda was the director of Discovery Science at ARTham Therapeutics Inc. She contributed to designing and executing two clinical proof of concept studies and clinical research. During her doctoral studies, she did her summer internship at Genentech Inc., where her passion for drug discovery and development was awakened. She started her career as a scientist at Takeda and worked on GPCR drug discovery, drug repositioning, and iPSC disease modeling, where she contributed to four project starts and one IND. She received her PhD from the Graduate School of Medicine, the University of Tokyo.

Tatsuhiko Fujimoto

Executive Director,
Chemistry and Alliance

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Dr. Tatsuhiko Fujimoto is SFG’s co-founder and Executive Director (Chemistry and Alliance). Over the past 20 years, Dr. Fujimoto has been dedicated to drug discovery through target identification for GPCR, enzymes and ion channels in neuroscience and metabolic disease therapeutic areas, drug design and synthesis as a medicinal chemist, and investment as a venture capitalist. Dr. Fujimoto's representative achievements was in drug discovery related to orexin science at Takeda. He entrepreneurially launched and led the orexin 2 receptor agonist project, known as a potential silver bullet for the treatment of narcolepsy (estimated annual sales potential of 40-60 billion USD). Dr. Fujimoto received his PhD from Osaka University.

Dnyaneshwar Warude

Executive Director,
Translational Sciences

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Dr. Dnyaneshwar Warude is SFG’s co-founder and Executive Director (Translational Sciences). He brings over 15 years of industry experience leading and building teams that have excellent track records of discovering and developing novel therapeutics. He dealt with multiple drug modalities including small molecule, engineered cell, antibody and peptide therapeutics. Prior to SFG, during his over 8 years tenure at Takeda, Dr. Dnyaneshwar led a Precision and Early Translation Medicine team at Immune-Oncology Drug Discovery Unit along with leading Asia-Pacific alliance and partnership activities. He also contributed in conceptualization of ART-001 with ARTham team. Before Takeda, he guided a team responsible for pre-clinical drug discovery for pain and inflammatory disorders at Lupin, Pune, India. Dr. Dnyaneshwar received his PhD from Interdisciplinary School of Health Science, Savitribai Phule Pune University, Pune.

Hiroshi Nagabukuro

Chief Executive Officer

linkedin

Dr. Hiroshi Nagabukuro is SFG’s co-founder, Chief Executive Officer (CEO) and board chair. Dr. Nagabukuro also serves as CEO of Juro Sciences, one of SFG’s portfolio companies. He brings over 25 years of industry experience, leading and building teams that have strong track records of discovering and developing novel therapeutics. Prior to SFG, he co-founded ARTham Therapeutics as COO/CSO followed by CEO role, and strategically and operationally led the company until its acquisition by Kaken Pharmaceutical in 2021. Before ARTham, Dr. Nagabukuro was Senior Director of Innovation & Entrepreneurship at Takeda, where he was heading the Entrepreneurship Venture Program and contributed launches of 9 different biotech companies. Prior to Takeda, he was Research Fellow at Merck Research Laboratories, where he led multiple target identification/validation and optimization programs and significantly contributed to the adrenergic β3 program, which resulted in the approval of vibegron for overactive bladder indication. Dr. Nagabukuro also serves as an Adjunct Professor at Tohoku University Hospital. He received his PhD from the University of Tokyo.

Akira Tanaka

Chief Scientific Officer

linkedin

Dr. Akira Tanaka is a SFG’s co-founder, serves as Chief Scientific Officer and a board director. Before the inception of SFG, Dr. Tanaka was the Vice President of Clinical Science at ARTham Therapeutics where he led the clinical development, conducted Phase I and Phase II studies for two products, and contributed to obtaining a POC for one of them. Prior to ARTham, he worked in preclinical drug discovery research as a pharmacologist at Takeda and thereafter in clinical development as a clinical scientist in gastrointestinal therapeutic area at Takeda Boston site. He received his PhD from the University of Tsukuba.

Kyohei Tanaka

Chief Financial Officer

linkedin

Mr. Kyohei Tanaka is SFG’s co-founder, serves as Chief Financial Officer and a board director. Before the inception of SFG, Mr. Tanaka led the M&A exit of ARTham Therapeutics in 2021 as the Financial Advisor. He started his career at KPMG Azsa Co., and from 2005, he engaged in advisory services for domestic and international M&A transactions at the investment banking division in Nikko Citigroup and CitigroupinJapan. Subsequently, he worked at a private equity fund in Japan before founding investment hub Corporation in 2018, where he serves as CEO, providing startups with support in financing, capital strategy, and M&A exits. Mr. Tanaka graduated from the Faculty of Agriculture at the University of Tokyo and is Japan’s Certified Public Accountant.

Steve Engen

Board Member

Steve brings over 25 years of senior executive level operating and transaction experience in the biopharmaceutical industry, with expertise in Japanese/Asian markets. In 1998, Steve established Mundipharma Japan and was president for nine years. From 2007, Steve served as CEO of Solasia Pharma, a cancer-focused development stage company. From 2012, he headed the Japanese operations of Shire Pharmaceuticals until 2014 when he established his own biopharma consultancy. After moving to Seattle in 2019, Steve established Renexes LLP to continue to facilitate transactions between Japanese and western biopharmaceutical companies. Steve and his wife have two daughters, and split time living in Tokyo and Seattle. Steve is fluent in written and spoken Japanese.

Ayako Kaiho

Auditor

Ms. Ayako Kaiho is the external company auditor. Having over thirty years of experiences in management and governance as a founder, a member of operating management team or a consultant to hospital, consumer product and financial industries, she has gained confidence in building and helping new business and securing the clarity and sustainability of operation. Her working experiences in the US also contributed to those projects with global talents of diversified expertise and background. Most recently Ms. Kaiho has served as the board member of Kato Sangyo, a prime market listed food wholesaler. She received the bachelor’s degree in finance from New York University.

Toshihiko Kamo

Entrepreneur in Residence

Mr. Toshihiko Kamo is an Entrepreneur in Residence at SFG. He has joined SFG since November 2023 as a secondee from JT. At JT, Mr. Kamo worked on non-clinical pharmacology research.

Toshiki Matsuoka

Entrepreneur in Residence

Toshiki Matsuoka is an Entrepreneur in Residence at SFG. He has joined SFG since April 2024 as a secondee from Daiichi Sanyo. Prior to joining SFG, he led discovery research including drug repositioning for psychiatric and neurological disorders, and translational research including biomarker identification and clinical research for target validation. Prior to that, he was involved in INDs and NDAs for several small molecule and biologics as a toxicology specialist. He completed his MS from the Graduate School of Medical Sciences, the University of Tsukuba, Japan.

Naoto Uemura

Professor
Oita University
Clinical Pharmacology & Therapeutics

Amy Broidrick

Biopharma Strategic Advisor

Yoichi Miyamae

Scientific Affairs Division
Shin Nippon
Biomedical Laboratories, Ltd. (SNBL)

Fujiko Takamura

Scientific Affairs Division
Shin Nippon
Biomedical Laboratories, Ltd. (SNBL)

Xiang Yao

Tanaka Urology Clinic
- Furuedai Suita

Satoshi Kitamura

CMC advisor

Companies

Portfolio

Program SFG Co Pre-clinical Phase 1 Phase 2
SFG-02    
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SFG SCIENCES Inc.

Yamashita-cho 24-8, Naka-kuYokohama 231-0023 JAPAN

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